Title: Intracellular concentration and transmembrane fluxes of sodium and potassium in erythrocytes of white normal male subjects with and without a family history of hypertension
Authors: Lijnen, Paul ×
M'Buyamba-Kabangu, J R
Fagard, Robert
Groeseneken, D R
Staessen, Jan A
Amery, A K #
Issue Date: 1984
Series Title: Journal of hypertension vol:2 issue:1 pages:25-30
Abstract: Compared with white normal males without a family history of hypertension (n = 43), red blood cells of white normal males with such a family history (n = 17) had a higher (P less than 0.01) intracellular sodium concentration (8.07 +/- 0.30 versus 7.33 +/- 0.17 mmol/l cells). This could be at least partly due to their lower (P less than 0.001) frusemide-sensitive sodium efflux rate (250 +/- 19 versus 424 +/- 23 mumol/l cells/h). Also their ouabain-resistant 86Rb-uptake (0.81 +/- 0.06 versus 0.97 +/- 0.03 mumol/l cells/h) was lower (P less than 0.05). Potassium concentration in the red blood cells was similar in both groups.
ISSN: 0263-6352
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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