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Title: Evidence that moment-to-moment variation in positive emotions buffer genetic risk for depression: a momentary assessment twin study
Authors: Wichers, Marieke C ×
Myin-Germeys, Inez
Jacobs, Nele
Peeters, Frenk
Kenis, Gunter
Derom, Cathérine
Vlietinck, Robert
Delespaul, Philippe
van Os, Jim #
Issue Date: Jun-2007
Series Title: Acta psychiatrica Scandinavica vol:115 issue:6 pages:451-7
Abstract: OBJECTIVE: The negative affective response to daily life stressors, which previous work suggest is a fundamental depression endophenotype, may be moderated by positive emotions. It was investigated whether positive affect (PA) buffers negative affect (NA) reactivity in response to stress and whether PA moderates the genetic predisposition to negative affect reactivity. METHOD: A total of 279 twin pairs participated in a momentary assessment study with the experience sampling method, collecting appraisals of stress and affect in the flow of daily life. Lifetime diagnoses of depression were obtained. RESULTS: There was a significant interaction between stress appraisal of event (STRESS) and PA in the association with NA. The interaction between proband PA, proband STRESS and co-twin lifetime depression showed that higher PA reduced the interaction between proband STRESS and co-twin lifetime depression. CONCLUSION: Positive emotions not only buffer against NA reactivity, but in addition attenuate genetic effects on negative mood bias in daily life.
ISSN: 0001-690X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical Genetics
Department of Human Genetics - miscellaneous
Clinical Genetics Section (-)
× corresponding author
# (joint) last author

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