Title: Diagnostic evaluation of PSA recurrence and review of hormonal management after radical prostatectomy
Authors: Van Poppel, Hendrik ×
Joniau, Steven
Van Cleynenbreugel, Ben
Mottaghy, F. M
Oyen, Raymond #
Issue Date: Jun-2009
Publisher: Stockton Press
Series Title: Prostate Cancer and Prostatic Diseases vol:12 issue:2 pages:116-123
Abstract: The aim of this review is to provide a discussion of the diagnostic evaluation of biochemical recurrence following radical prostatectomy (RP) and an overview of the postoperative hormonal treatment (HT) options. As no randomized trials in the clinical setting of postoperative prostate-specific antigen recurrence have been reported, there is no conclusive evidence that HT after RP will prolong survival or reduce morbidity. Non-traditional approaches, such as intermittent androgen deprivation, non-steroidal anti-androgens and combination of finasteride and nonsteroidal anti-androgen, are investigated and may be acceptable options. Combinations of HT with radiotherapy and/or chemotherapy for treatment of recurrent prostate cancer are under study. Prostate Cancer and Prostatic Diseases (2009) 12, 116-123; doi:10.1038/pcan.2009.3; published online 24 February 2009
ISSN: 1365-7852
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Urology Section (-)
× corresponding author
# (joint) last author

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