Title: Ancient mitochondrial DNA from Malaysian hair samples: some indications of Southeast Asian population movements
Authors: Ricaut, Fran├žois-Xavier ×
Bellatti, Maggy
Lahr, Marta Mirazon #
Issue Date: 2006
Publisher: Alan R. Liss
Series Title: American Journal of Human Biology vol:18 issue:5 pages:654-667
Abstract: The late Pleistocene and early Holocene population history of Southeast Asia is
not well-known. Our study provides new data on mitochondrial DNA (mtDNA) lineages of the
aboriginal inhabitants of the Malay Peninsula, and through an extensive comparison to the
known mtDNA diversity in Southeast and East Asia, provides some new insights into the origins
and historical geography of certain mtDNA lineages in the region. We extracted DNA from hair
samples (dating back 100 years) preserved in the Duckworth Collection and belonging to two
Peninsular Malaysian individuals identified as ‘‘Negrito.’’ Ancient DNA was analyzed by sequencing
hypervariable region I (HVS-I) of the mtDNA control region and the mtDNA region V length
polymorphism. The results show that the maternal lineages of these individuals belong to a
recently defined haplogroup B sub-branch called B4c2. A comparison of mitochondrial haplotypes
and haplogroups with those of 10,349 East Asian individuals indicates their very restricted geographical
distribution (southwestern China, Southeast Asia Peninsula, and Indonesia). Recalculation
of the B4c2 age across all of East Asia (13,000 years) and in different subregions/populations
suggests its rapid diffusion in Southeast Asia between the end of the Last Glacial Maximum and
the Neolithic expansion of the Holocene.
ISSN: 1042-0533
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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