Title: Nonlinear propagation effects on broadband attenuation measurements and its implications for ultrasonic tissue characterization
Authors: D'hooge, Jan ×
Bijnens, Bart
Nuyts, Johan
Gorce, J M
Friboulet, D
Thoen, Jan
Van de Werf, Frans
Suetens, Paul #
Issue Date: Aug-1999
Series Title: The Journal of the Acoustical Society of America vol:106 issue:2 pages:1126-1133
Abstract: A study is presented in which the influence of the pressure amplitude of the incident pulse on the estimated frequency dependency of the attenuation coefficient is shown. First, the effect is demonstrated with a simple theoretical model for both transmission and reflection measurements. Simulations show that for both measurement techniques a high-amplitude incident pulse results in a biased estimate of the attenuation coefficient due to nonlinear interaction of the different frequency components of the incident pulse. It is shown that in transmission and reflection measurements the biases have opposite signs. The effect of bandwidth, central frequency, and phase of the incident pulse on this bias is investigated. Second, the effect is demonstrated both in vitro, using a broadband through-transmission substitution technique on a tissue mimicking gelatine phantom, and in vivo, using reflection measurements with standard clinical equipment. The experimental results agree well with the theoretical model. The relevance of this study for ultrasonic tissue characterization is shown.
ISSN: 0001-4966
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Nuclear Medicine & Molecular Imaging
Soft Matter and Biophysics
Cardiovascular Imaging and Dynamics
ESAT - PSI, Processing Speech and Images
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science