Title: FV100 as a new approach for the possible treatment of varicella-zoster virus infection
Authors: McGuigan, Christopher ×
Balzarini, Jan #
Issue Date: Oct-2009
Publisher: Oxford University Press
Series Title: The Journal of Antimicrobial Chemotherapy vol:64 pages:671-673
Abstract: FV100 is a promising new agent with extreme potency and specificity for varicella-zoster virus (VZV). It is the valyl ester pro-drug of Cf1743, the lead clinical candidate among the highly lipophilic bicyclic nucleoside analogue (BCNA) family discovered in Cardiff/Leuven. Cf1743 is unique amongst antivirals in terms of its structure and lipophilicity. It is exquisitely potent and selective for human VZV. FV100 has recently entered a randomized, controlled Phase II clinical trial for the treatment of shingles, sponsored by Inhibitex.
ISSN: 0305-7453
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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