Title: Synthesis and oxidative cyclization of 2-arylhydrazono-2-cyanoacetamidines to 5-amino-2-aryl-2H-[1,2,3]triazole-4-carbonitrile
Authors: Bel'skaya, Natalia P ×
Demina, Marina A
Sapognikova, Svetlana G
Fan, Zhi-Jin
Zhang, Hai-Ke
Dehaen, Wim
Bakulev, Vasiliy A #
Issue Date: 2008
Publisher: Arkat usa inc
Series Title: Arkivoc pages:9-21
Abstract: A general and convenient method for the synthesis of 2-arylhydrazono-2-cyanoacetamidines, containing either a cytisine or tryptamine moiety, or other secondary and primary amines was elaborated. A series of 5-amino-2-aryl-2H-[1,2,3]-triazole-4-carbonitriles was successfully prepared by oxidation of these amidines with copper acetate in pyridine. The screening of the biological activity of the synthesized triazoles and amidines have shown that, some of these compounds possess fungicidal activity at concentrations of 50 mu g/mL against some fungi tested.
ISSN: 1551-7004
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science