Title: Amphiphilic Porphyrins for Second Harmonic Generation Imaging
Authors: Reeve, James E ×
Collins, Hazel A
De Mey, Kurt
Kohl, Michael M
Thorley, Karl J
Paulsen, Ole
Clays, Koen
Anderson, Harry L #
Issue Date: Mar-2009
Publisher: Amer chemical soc
Series Title: Journal of the American Chemical Society vol:131 issue:8 pages:2758-+
Abstract: Amphiphilic donor-acceptor meso-ethynyl porphyrins with polar pyridinium electron-acceptor head groups and hydrophobic dialkyl-aniline electron donors have high molecular hyperpolarizabilities (as measured by hyper-Rayleigh scattering) and high affinities for biological membranes. When bound to water droplets in dodecane, or to the plasma membranes of living cells, they can be used for second harmonic generation (SHG) microscopy; an incident light of wavelength 840 nm generates a strong frequency-doubled signal at 420 nm. Copper(II) and nickel(II) porphyrin complexes give similar SHG signals to those of the free-base porphyrins, while exhibiting no detectable two-photon excited fluorescence.
ISSN: 0002-7863
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Imaging and Photonics
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science