Title: Alterations in sodium metabolism as an etiological model for hypertension
Authors: Lijnen, Paul # ×
Issue Date: Jun-1995
Series Title: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy vol:9 issue:3 pages:377-99
Abstract: An adequate matching for race, sex, stage of the menstrual cycle, family history of hypertension, and the amount of sodium and other electrolytes in the diet should be a prerequisite for valid conclusions when interpreting the erythrocyte concentration and fluxes of sodium in essential hypertensive patients in comparison with normal subjects. Alterations in intracellular sodium concentration and transmembrane sodium transport systems as causes of essential hypertension are postulated. This review article describes how this abnormal sodium and calcium metabolism translates into increased systemic vascular resistance through altered vasoactive responses and/or vasculature structural changes.
ISSN: 0920-3206
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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