Title: Synthesis of 22-oxaspiro[4.5]decane CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D-3
Authors: De Buysser, Frederik
Verlinden, Lieve
Verstuyf, Annemieke
De Clercq, Pierre J # ×
Issue Date: Jul-2009
Publisher: Pergamon Press
Series Title: Tetrahedron Letters vol:50 issue:28 pages:4174-4177
Abstract: In search of analogs of 1 alpha,25-dihydroxyvitamin D-3 featuring a dissociation of calcemic and other activities, a series of stereoisomeric 19-nor-22-oxa derivatives, characterized by a spiro[4.5]decane cyclic system instead of the classical CD-ring system, have been synthesized in an enantioselective way. (C) 2009 Elsevier Ltd. All rights reserved.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
× corresponding author
# (joint) last author

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