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Title: Effects of homocysteine on the cellular responses of murine endothelial cells cultured in vitro
Authors: Tacheny, A ×
dos Santos, S
Huet, A-C
van Steenbrugge, M
Michiels, C
Holvoet, Paul
Raes, M #
Issue Date: Nov-2002
Series Title: Annals of the New York Academy of Sciences vol:973 pages:550-4
Abstract: Homocysteine, derived from the metabolism of methionine, is claimed as a proatherogenic factor that leads to vascular dysfunction. To gain better insight into the molecular mechanisms involved, homocysteine was tested on a model of murine endothelial cells cultured in vitro, using a prototype DNA chip. The DNA chip was designed to follow the expression at the mRNA level of some major proinflammatory genes; TNF-alpha was used as a positive control.
ISSN: 0077-8923
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Atherosclerosis and Metabolism (-)
× corresponding author
# (joint) last author

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