Title: Comparison of Caenorhabditis elegans NLP peptides with arthropod neuropeptides
Authors: Husson, Steven ×
Lindemans, Marleen
Janssen, Tom
Schoofs, Liliane #
Issue Date: Apr-2009
Publisher: Elsevier
Series Title: Trends in Parasitology vol:25 issue:4 pages:171-181
Abstract: Neuropeptides are small messenger molecules that can be found in all metazoans, where they govern a diverse array of physiological processes. Because neuropeptides seem to be conserved among pest species, selected peptides can be considered as attractive targets for drug discovery. Much can be learned from the model system Caenorhabditis elegans because of the availability of a sequenced genome and state-of-the-art postgenomic technologies that enable characterization of endogenous peptides derived from neuropeptide-like protein (NLP) precursors. Here, we provide an overview of the NLP peptide family in C. elegans and discuss their resemblance with arthropod neuropeptides and their relevance for anthelmintic discovery.
ISSN: 1471-4922
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

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