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Title: APRP, the second peptide encoded by the adipokinetic hormone gene(s), is highly conserved in evolution: a role in control of ecdysteroidogenesis?
Authors: De Loof, Arnold ×
Vandersmissen, Tim
Huybrechts, Jurgen
Landuyt, Bart
Baggerman, Geert
Clynen, Elke
Lindemans, Marleen
Husson, Steven
Schoofs, Liliane #
Issue Date: Apr-2009
Publisher: New York Academy of Sciences
Series Title: Annals of the New York Academy of Sciences vol:1163 issue:Trends in Comparative Endocrinology and Neurobiology pages:376-378
Abstract: Since the early days of cloning the first adipokinetic hormone (AKH) gene, researchers recognized that this gene also codes for a joining region and for a second peptide called adipokinetic hormone precursor related peptide (APRP). In species with more than one AKH gene, such as locusts, APRPs can form both homodimers and heterodimers. Database analysis showed that APRPs might belong to the ancient family of growth hormone releasing factor but they still are functionally orphan. We investigated whether some of the APRP forms play a role in control of reproduction or/and growth via stimulation of ecdysteroidogenesis.
URI: 
ISSN: 0077-8923
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
Microbial and Molecular Systems - miscellaneous
× corresponding author
# (joint) last author

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