Title: Molecular and cellular MR imaging: Potentials and challenges for neurological applications
Authors: Hoehn, Mathias ×
Himmelreich, Uwe
Kruttwig, Klaus
Wiedermann, Dirk #
Issue Date: May-2008
Publisher: Society for Magnetic Resonance Imaging
Series Title: Journal of Magnetic Resonance Imaging vol:27 issue:5 pages:941-954
Abstract: This review presents the state of the art of molecular MRI and its application to experimental neurology and neuroscience. We do not repeat a broad, comprehensive overview over the rapidly growing literature in the field of "molecular MRL" which is achieved by several recent reviews. Instead, we focus here on the potential of this imaging technique and its challenges to achieve useful new information in various fields of application with the aim of visualizing cellular processes in the brain, in both the physiological and pathophysiological context. Particular attention will be given to the visualization of cells grafted into the brain. For this goal, the recent most exciting studies are selected as the best examples to elucidate the method's fast expanding potentials. Attention is also given to the aspects of producing synergies by combining molecular MRI with other molecular imaging modalities, thus generating the most complex pictures of cellular and molecular events in the brain under in vivo conditions.
ISSN: 1053-1807
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Biomedical MRI
× corresponding author
# (joint) last author

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