Title: Review of the Major Hypertension Trials in the Elderly
Authors: Staessen, Jan ×
Fagard, Robert
Lijnen, Paul
Van Hoof, R
Amery, A #
Issue Date: 1990
Publisher: Martinus Nijhoff Pub.
Series Title: Cardiovascular drugs and therapy vol:4 Suppl 6 pages:1237-47
Abstract: The different intervention trials in elderly hypertensives are compatible with the hypothesis that hypotensive drug treatment can decrease cardiovascular mortality mainly by decreasing cerebrovascular mortality. A decrease in the fatal and nonfatal cardiovascular event rate is mainly due to a decrease in cerebrovascular events. It is not established whether hypotensive drug treatment is advisable in symptomless patients with isolated systolic hypertension and in patients with uncomplicated hypertension above age 80. A sudden reduction in blood pressure should be avoided, but whether a progressive reduction of systolic blood pressure below 140 mmHg and of diastolic blood pressure below 85 mmHg is dangerous or advantageous remains to be established.
ISSN: 0920-3206
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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