Title: Propagation and titration of murine cytomegalovirus in a continuous bone marrow-derived stromal cell line (M2-10B4)
Authors: Lutarewych, M A ×
Quirk, M R
Kringstad, B A
Lin, Wei
Verfaillie, Catherine
Jordan, M C #
Issue Date: Nov-1997
Series Title: Journal of virological methods vol:68 issue:2 pages:193-8
Abstract: Murine cytomegalovirus (MCMV) can only be propagated effectively in mouse embryo fibroblast (MEF) cells. We demonstrate that MCMV replicates significantly better in M2-10B4 cells, a continuous line of murine bone marrow stromal cells. M2-10B4 cells were also comparable to MEF cells for detection of small amounts of MCMV reactivating from latently infected spleen explants. M2-10B4 cells will be very useful for studies of MCMV pathogenesis.
ISSN: 0166-0934
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Interdepartemental Stem Cell Institute (-)
Physiology Section (-)
× corresponding author
# (joint) last author

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