Title: Acute changes in the renin-angiotensin-aldosterone system, catecholamines and prostaglandins during captopril in man
Authors: Lijnen, Paul ×
Verschueren, L J
Fagard, Robert
Staessen, Jan A
Amery, A #
Issue Date: Dec-1980
Series Title: Methods and findings in experimental and clinical pharmacology vol:2 issue:6 pages:293-301
Abstract: The acute hypotensive effect of 25 mg captopril was investigated in 26 hypertensive patients (11 essential and 15 with renal arterial disease). Intra-arterial blood pressure was recorded continuously and arterial blood was sampled for renin, angiotensin I and II, aldosterone, kininase II, catecholamines and prostaglandins. Captopril provoked increases in plasma renin activity, active and total plasma renin concentration and angiotensin I; decreases in plasma kininase II activity, angiotensin II, aldosterone, prostaglandins E2 and F2 alpha and no changes in plasma (nor)adrenaline, dopamine and inactive renin concentration.
ISSN: 0379-0355
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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