ITEM METADATA RECORD
Title: Pravastatin has no direct effect on transmembrane cationic transport systems in human erythrocytes and platelets
Authors: Lijnen, Paul ×
Petrov, Victor
Amery, A #
Issue Date: Jan-1994
Series Title: European journal of clinical pharmacology vol:47 issue:3 pages:281-3
Abstract: In vitro incubation of human erythrocytes and platelets with the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin in the concentration range 1 nM to 10 microM did not affect the activity of the Na(+)-K(+)-pump, Na(+)-K(+)-cotransport or Na(+)-Li(+)-countertransport, or the ground membrane leak for Na+ and K+. The data indicate that pravastatin has no direct effect on transmembrane cationic transport systems in red blood cells or platelets.
ISSN: 0031-6970
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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