Title: Synthesis of 2 '-O-alpha-D-ribofuranosyladenosine, monomeric unit of poly(ADP-ribose)
Authors: Mikhailov, Sergey N
Kulikova, Irina V
Nauwelaerts, Koen
Herdewijn, Piet # ×
Issue Date: Mar-2008
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:64 issue:12 pages:2871-2876
Abstract: The first chemical synthesis of 2'-O-alpha-D-ribofuranosyladenosine, monomeric unit of poly(ADP-ribose), has been achieved starting from 3',5'-O-bis protected 9-(2-O-alpha-D-arabinofuranosyl-beta-D-ribofuranosyl)-adenine. Configurational inversion of 2'-hydroxyl group of arabinose moiety was performed by oxidation-reduction sequence. (C) 2008 Elsevier Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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