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Title: Non-nucleoside HIV-1 reverse transcriptase inhibitors Part 13. Synthesis of fluorine-containing diaryltriazine derivatives for in vitro anti-HIV evaluation against wild-type strain
Authors: Xiong, Yuan-Zhen ×
Chen, Fen-Er
Balzarini, Jan
De Clercq, Erik
Pannecouque, Christophe #
Issue Date: 2009
Publisher: Verlag Helvetica Chimica Acta
Series Title: Chemistry & Biodiversity vol:6 issue:4 pages:561-568
Abstract: A series of diaryltriazine derivatives modified at C(2) of the triazine ring with a fluorinated phenyl group has been synthesized and tested for the ability to inhibit HIV-1 replication. Most of these F-containing compounds showed low-to-moderate anti-HIV activity in MT-4 cells.
ISSN: 1612-1872
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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