A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes
Chamorro, Cristina × Kruijtzer, John A. W Farsaraki, Marina Balzarini, Jan Liskamp, Rob M. J #
Royal Society of Chemistry
Chemical Communications issue:7 pages:821-823
In this Communication, the access to three different peptide loops attached to a small triazacyclophane (TAC) scaffold molecule for the mimicry of discontinuous epitopes present in, for example, antibodies is described for the first time.