Gene inactivation of U-PA or adenoviral gene transfer of tissue inhibitor of metalloproteinases-1 impedes cardiac hypertrophy and fibrosis, but improves cardiac function during hypertension in mice

Heymans, Stephane; Luttun, Aernout; Carmeliet, Peter; Collen, Desire

Circulation

Gene inactivation of U-PA or adenoviral gene transfer of tissue inhibitor of metalloproteinases-1 impedes cardiac hypertrophy and fibrosis, but improves cardiac function during hypertension in mice

Author:

Heymans, Stephane

Luttun, Aernout ; Carmeliet, Peter ; Collen, Desire

Keywords:

Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Peripheral Vascular Disease, Cardiovascular System & Cardiology, 1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, 1117 Public Health and Health Services, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology, 3202 Clinical sciences, 4207 Sports science and exercise

Circulation Gene inactivation of U-PA or adenoviral gene transfer of tissue inhibitor of metalloproteinases-1 impedes cardiac hypertrophy and fibrosis, but improves cardiac function during hypertension in mice

Author:

Keywords:

Circulation

Gene inactivation of U-PA or adenoviral gene transfer of tissue inhibitor of metalloproteinases-1 impedes cardiac hypertrophy and fibrosis, but improves cardiac function during hypertension in mice