Title: Detection of Odorous Compounds in Breath
Authors: Van den Velde, Sandra ×
van Steenberghe, Daniel
Van hee, P
Quirynen, Marc #
Issue Date: Mar-2009
Publisher: Sage publications inc
Series Title: Journal of Dental Research vol:88 issue:3 pages:285-289
Abstract: Previous studies have demonstrated that hydrogen sulfide and methyl mercaptan play a major role in oral malodor. In the present study, we tested the hypothesis that other compounds found in mouth air can also contribute to halitosis. Mouth air of 40 healthy volunteers and 40 persons with halitosis was analyzed and compared by gas chromatography-mass spectrometry, two sulfur monitors, and organoleptically. Nearly 700 different compounds were detected. Hydrogen sulfide, methyl mercaptan, dimethyl sulfide, di- and trisulfide were increased in persons with breath odor. These compounds were all significantly correlated with the organoleptic score. We concluded that hydrogen sulfide, methyl mercaptan and, to a much lesser extent, dimethyl sulfide, di- and trisulfide can contribute to oral malodor. The role of other compounds, such as amines and organic acids, seems insignificant.
ISSN: 0022-0345
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Periodontology
× corresponding author
# (joint) last author

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