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Title: Administration of human fibroblast interferon in chronic hepatitis-B infection
Authors: Desmyter, Jan ×
De Groote, Jan
Desmet, V J
Billiau, Alfons
Ray, M B
Bradburne, A F
Edy, V G
De Somer, P #
Issue Date: Sep-1976
Series Title: Lancet vol:2 issue:7987 pages:645-7
Abstract: One patient with hepatitis-B surface antigen (HBsAg)-positive chronic aggressive hepatitis, and two chimpanzee carriers of HBsAg, were each given seven doses of 10(7) I.U. of human fibroblast interferon over two weeks. The main differnce observed after treatment was a depression of the nucleocapsid hepatitis-0 core antigen in the liver, indicating that hepatitis-B virus infection is sensitive to interferon. Except for a short febrile reaction, no undesirable effects were seen after the administration of human fibroblast interferon which has not been previously given to man.
ISSN: 0140-6736
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hepatology
Laboratory of Immunobiology (Rega Institute)
× corresponding author
# (joint) last author

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