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Title: Immunoelectron microscopic investigation of HLA-DR-positive dendritic cells at the dermo-epidermal junction in skin disorders associated with the deposition of immune complexes
Authors: Drijkoningen, Maria ×
De Vos, Rita
Peeters, C
Degreef, Hugo
Desmet, Valeer #
Issue Date: Jan-1986
Series Title: Ultrastructural pathology vol:10 issue:2 pages:123-8
Abstract: HLA-DR-positive dendritic cells present at the dermo-epidermal junction in skin disorders associated with the deposition of immunoglobulins and/or complement factors in the skin biopsy are investigated ultrastructurally. They demonstrate long, slender cytoplasmic processes, an indented nucleus, and strikingly dilated cisternae of the endoplasmic reticulum. HLA-DR antigen is present on the plasma membrane and within some of the dilated cisternae. These findings further support our previously formulated hypothesis that these cells represent a functionally active stage of antigen-presenting cells.
ISSN: 0191-3123
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Dermatology
Translational Cell & Tissue Research
Interdepartmental Platform Hospital Care
× corresponding author
# (joint) last author

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