Title: [Rickets resistant to calcitropic hormones]
Authors: Vainsel, M ×
Bouillon, Roger #
Issue Date: Nov-1995
Series Title: Revue médicale de Bruxelles vol:16 issue:5 pages:364-7
Abstract: Resistance to vitamin D is known since a long time but was erroneously ascribed to phosphate deficiency (phosphate diabetes or deficiency in tubular phosphate reabsorption). True vitamin D resistance can either be due to lack of the receptor itself or to structural abnormality in the hormone -or DNA-binding site of the receptor whereas in a few cases post-receptor resistance has been documented. In view of the therapeutic consequences, diagnosis of vitamin D resistance is needed in every case of rickets not due to simple vitamin D deficiency. Such cases can be easily recognized by normal 25-hydroxyvitamin D concentration in the presence of biochemical, radiological or/and histological signs of rickets.
ISSN: 0035-3639
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
× corresponding author
# (joint) last author

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