Title: D-aspartate oxidase, a peroxisomal enzyme in liver of rat and man
Authors: Van Veldhoven, Paul P ×
Brees, C
Mannaerts, Guy #
Issue Date: Jan-1991
Publisher: Elsevier science bv
Series Title: Biochimica et Biophysica Acta vol:1073 issue:1 pages:203-208
Abstract: By means of subcellular fractionation D-aspartate oxidase was shown to be localized in peroxisomes in rat and human liver. The oxidase from both sources was most active on D-aspartate and N-methyl-D-aspartate. In different rat tissues, the highest enzyme activity was found in kidney, followed by liver and brain. In these tissues, oxidase activities became detectable 1-4 days after birth, reaching adult values after 4 weeks. Analysis of liver samples from patients with Zellweger syndrome, a generalized peroxisomal dysfunction, demonstrated no significant deficiency of this particular oxidase.
ISSN: 0006-3002
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Lipid Biochemistry and Protein Interactions
× corresponding author
# (joint) last author

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