Title: Possible association of nicastrin polymorphisms and Alzheimer disease in the Finnish population
Authors: Helisalmi, S
Dermaut, Bart
Hiltunen, M
Mannermaa, A
Van den Broeck, M
Lehtovirta, M
Koivisto, AM
Iivonen, S
Cruts, M
Soininen, H
Van Broeckhoven, C # ×
Issue Date: Jul-2004
Publisher: Lippincott williams & wilkins
Series Title: Neurology vol:63 issue:1 pages:173-175
Abstract: The authors previously reported that genetic variation in the gene coding for nicastrin (NCSTN) modified risk for familial early-onset Alzheimer disease (AD) in a Dutch population-based sample. Risk was highest in patients without an APOE epsilon4 allele. Here, they evaluated if NCSTN polymorphisms increased risk of AD in the eastern Finnish population. A significant difference in one haplotype was observed in AD patients without the APOE epsilon4 allele.
ISSN: 0028-3878
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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