Title: Sequential administration of gemtuzumab ozogamicin and conventional chemotherapy as first line therapy in elderly patients with acute myeloid leukemia: a phase II study (AML-15) of the EORTC and GIMEMA leukemia groups
Authors: Amadori, S ×
Suciu, S
Willemze, R
Mandelli, F
Selleslag, D
Stauder, R
Denzlinger, C
Leone, G
Fabris, P
Muus, P
Vignetti, M
Hagemeijer-Hausman, Anne
Beeldens, F
Anak, O
De Witte, T #
Issue Date: Aug-2004
Publisher: Ferrata storti foundation
Series Title: Haematologica vol:89 issue:8 pages:950-956
Abstract: Background and Objectives. Acute myeloid leukemia (AML) in the elderly is associated with low rates of response to conventional chemotherapy and long-term survival, highlighting the need for innovative treatment strategies. Gemtuzumab ozogamicin (GO) is an immunoconjugate that has shown activity in relapsed AML with a favorable safety profile. The aim of-this collaborative trial was to assess the feasibility, safety, and antileukemic activity of administering GO followed by conventional chemotherapy as first line therapy in patients aged 61-75 years with AML.
ISSN: 0390-6078
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical Genetics Section (-)
× corresponding author
# (joint) last author

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