Title: Exons, introns, and DNA thermodynamics
Authors: Carlon, Enrico ×
Lejard Malki, M
Blossey, R #
Issue Date: May-2005
Publisher: American physical soc
Series Title: Physical review letters vol:94 issue:17 pages:-
Article number: 0
Abstract: The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e., stretches of DNA which do not carry useful information for protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from genomic DNA by removing all introns. A clear correspondence is observed between exons and melting domains. This finding may provide new insights into the physical mechanisms underlying the evolution of genes.
Description: See also the Physical Review Focus story
ISSN: 0031-9007
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Theoretical Physics Section
× corresponding author
# (joint) last author

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