Title: Regulation of vitamin D homeostasis: implications for the immune system
Authors: van Etten, Evelyne ×
Stoffels, Katinka
Gysemans, Conny
Mathieu, Chantal
Overbergh, Lutgart #
Issue Date: Oct-2008
Publisher: International Life Sciences Institute and Nutrition Foundation
Series Title: Nutrition Reviews vol:66 issue:10 pages:S125-S134
Conference: Marabou Symposium on the Changing Faces of Vitamin D edition:22 location:Stockholm, Sweden date:1-3 june 2007
Abstract: Vitamin D homeostasis in the immune system is the focus of this review. The production of both the activating (25- and 1 alpha-hydroxylase) and the metabolizing (24-hydroxylase) enzymes by cells of the immune system itself, indicates that 1,25(OH)(2)D-3 can be produced locally in immune reaction sites. Moreover, the strict regulation of these enzymes by immune signals is highly suggestive for an autocrine/paracrine role in the immune system, and opens new treatment possibilities. (C) 2008 International Life Sciences Institute.
ISSN: 0029-6643
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
Molecular and Vascular Biology
Medical Clerkships Centers
× corresponding author
# (joint) last author

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