Published by the University of Chicago Press for the Infectious Diseases Society of America
The Journal of Infectious Diseases vol:199 issue:10 pages:1457-1460
In this observational study mumps-specific in vitro lymphoproliferation was measured in 24 subjects with low and 24 subjects with high antibody titers who received the last vaccine dose up to 16 years before. Overall, a significant lymphoproliferative response was found in 32 subjects (66.7%), namely in 54.2% of those with low and in 79.2% of the subjects with high antibody titers. The mean stimulation index (SI) in those with low and high antibody titers was 4.47 and 8.31, respectively (p=0.032). Mumps vaccine induced cell-mediated immunity appears to be more persistent than the antibody response.