Title: Evaluation of Cellular Immunity to Mumps in Immunized Individuals with and without Circulating Antibodies up to 16 Years after Last Vaccination
Authors: Vandermeulen, Corinne ×
Clement, Frédéric
Roelants, Mathieu
Van Damme, Pierre
Hoppenbrouwers, Karel
Leroux-Roels, Geert #
Issue Date: 15-May-2009
Publisher: Published by the University of Chicago Press for the Infectious Diseases Society of America
Series Title: The Journal of Infectious Diseases vol:199 issue:10 pages:1457-1460
Abstract: In this observational study mumps-specific in vitro lymphoproliferation was measured in 24 subjects with low and 24 subjects with high antibody titers who received the last vaccine dose up to 16 years before. Overall, a significant lymphoproliferative response was found in 32 subjects (66.7%), namely in 54.2% of those with low and in 79.2% of the subjects with high antibody titers. The mean stimulation index (SI) in those with low and high antibody titers was 4.47 and 8.31, respectively (p=0.032). Mumps vaccine induced cell-mediated immunity appears to be more persistent than the antibody response.
ISSN: 0022-1899
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Youth Health (-)
Environment and Health - miscellaneous
× corresponding author
# (joint) last author

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