ITEM METADATA RECORD
Title: Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients
Authors: Kuypers, Dirk ×
de Jonge, Hylke
Naesens, Maarten
Vanrenterghem, Yves #
Issue Date: Oct-2008
Publisher: Lippincott williams & wilkins
Series Title: Pharmacogenetics and genomics vol:18 issue:10 pages:861-868
Abstract: Objective Drug interactions between tacrolimus and azole antifungals are characterized by a large clinical variability. The aim of this study was to examine the influence of the CYP3A4, CYP3A5, and MDR1 single nucleotide polymorphisms on changes in tacrolimus exposure and dosing in renal allograft recipients treated with fluconazole.
ISSN: 1744-6872
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Nephrology
Department of Microbiology & Immunology - miscellaneous
× corresponding author
# (joint) last author

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