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Title: Pathophysiology of Cyclic Hemorrhagic Ascites and Endometriosis
Authors: Ussia, Anastasia ×
Betsas, George
Corona, Roberta
De Cicco, Carlo
Koninckx, Philippe #
Issue Date: Nov-2008
Publisher: Elsevier science inc
Series Title: Journal of minimally invasive gynecology vol:15 issue:6 pages:677-681
Abstract: Massive hemorrhagic ascites (4470 mL, range 1-10 L) in women with endometriosis is a rare condition occurring predominantly in black women. Of the 43 case reports published, 42 are compatible with the hypothesis that the hemorrhagic ascites is predominantly a consequence of excessive ovarian transudation similar to a Meigs syndrome. Indeed, bilateral ovariectomy cures the condition without recurrences, whereas after unilateral ovariectomy or cystectomy recurrence rate is more than 50%; during ovarian suppression by luteinizing hormone-releasing hormone agonist ascites disappears, but reappears after treatment. Superficial pelvic endometriosis also contributes to the ascites because after superficial endometriosis destruction the recurrence rate is only 4 in 14. Based on these data, it is suggested, to scrutinize the ovaries for tumors given the analogy with Meigs syndrome. In women desiring fertility, conservative treatment with destruction of endometriosis only can be attempted given the cure rate of some 20%. It is unknown what the effect of ovulation induction would be. Journal of Minimally Invasive Gynecology (2008) 15, 677-681 (C) 2008 AAGL. All rights reserved.
URI: 
ISSN: 1553-4650
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Basic Research in Gynaecology Section (-)
× corresponding author
# (joint) last author

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