Title: Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling
Authors: Loyer, Xavier ×
Gomez, Ana Maria
Milliez, Paul
Fernandez-Velasco, Maria
Vangheluwe, Peter
Vinet, Laurent
Charue, Dominique
Vaudin, Emilie
Zhang, Wei
Sainte-Marie, Yannis
Robidel, Estelle
Marty, Isabelle
Mayer, Bernd
Jaisser, Frederic
Mercadier, Jean-Jacques
Richard, Sylvain
Shah, Ajay M
Benitah, Jean-Pierre
Samuel, Jane-Lise
Heymes, Christophe #
Issue Date: Jun-2008
Publisher: Lippincott williams & wilkins
Series Title: Circulation vol:117 issue:25 pages:3187-3198
Abstract: Background - Defects in cardiomyocyte Ca2+ cycling are a signature feature of heart failure (HF) that occurs in response to sustained hemodynamic overload, and they largely account for contractile dysfunction. Neuronal nitric oxide synthase (NOS1) influences myocyte excitation-contraction coupling through modulation of Ca2+ cycling, but the potential relevance of this in HF is unknown.
ISSN: 0009-7322
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Cellular Transport Systems
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science