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Title: RNAi-based treatment of HIV/AIDS: Current status and perspectives
Authors: Vandekerchove, Linos
De Rijck, Jan
Christ, Frauke
Gijsbers, Rik
Debyser, Zeger # ×
Issue Date: 2006
Publisher: Elsevier
Series Title: Drug Discovery Today. Therapeutic Strategies vol:3 issue:2 pages:227-235
Abstract: The global HIV epidemic kills around 3 million people annually and attempts to control further spread have been of limited success. The efficacy of antiviral drug therapy has been limited by toxicity and viral resistance. Thus, alternative therapies need to be explored. Recently RNA interference (RNAi) has been shown to efficiently inhibit gene expression in a sequence-specific manner. Therefore, RNAi mediated treatment of HIV is a promising alternative for future therapy of HIV/AIDS.
ISSN: 1740-6773
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

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