Title: Angiotensin II levels in hypertensive and normotensive pregnancies
Authors: Hanssens, Myriam ×
Keirse, M J
Spitz, Bernard
Van Assche, Frans Andre #
Issue Date: Feb-1991
Publisher: British Journal of Obstetrics and Gynaecology
Series Title: British Journal of Obstetrics and Gynaecology vol:98 issue:2 pages:155-61
Abstract: We measured circulating angiotension II by radioimmunoassay in women with pregnancy-induced hypertension (n = 54), and compared these values with those obtained in women with normal pregnancy (n = 18) and in non pregnant women (n = 20). Pregnant women had statistically significantly higher plasma angiotensin II [mean (SD): 41.3 (12.6) pg/ml] than non-pregnant women [29.2 (11.3) pg/ml; P less than 0.004]. Angiotensin II concentrations in women with pregnancy-induced hypertension [mean (SD): 31.7 (16.2) pg/ml] were, on average, 25% lower than in normal pregnancy (P less than 0.003) and resembled those obtained in non-pregnant women. The lowest angiotensin II levels were found in women with more severe forms of pregnancy-induced hypertension, such as proteinuric or superimposed pregnancy-induced hypertension. Review of the published studies on angiotensin II and our data suggest that the conflict among studies on angiotensin II levels in pregnancy-induced hypertension is largely due to the heterogeneity of the study populations in the various reports.
ISSN: 0306-5456
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Woman - Miscellaneous (-)
Pathophysiology of Pregnancy Section (-)
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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