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Title: Tobacco smoking impairs the local immunosurveillance in the uterine cervix. An immunohistochemical study
Authors: Poppe, Willy ×
Ide, P S
Drijkoningen, M P
Lauweryns, J M
Van Assche, Frans Andre #
Issue Date: Jan-1995
Series Title: Gynecologic and obstetric investigation vol:39 issue:1 pages:34-8
Abstract: Previous reports have supported an association between tobacco smoking and cervical neoplasia. Our observations show an association between smoking and a reduction of the numerical densities of Langerhans cells and of helper/inducer T lymphocytes in the squamous epithelia of the transformation zone of the uterine cervix. This suggests a local impairment of cell-mediated immunity by smoking. This immunosuppressive effect could support the concept that smoking is an independent risk factor for cervical neoplasia.
ISSN: 0378-7346
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Woman - Miscellaneous (-)
Basic Research in Gynaecology Section (-)
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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