Title: Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: The GENOMOS study
Authors: Ralston, Stuart H ×
Uitterlinden, Andre G
Brandi, Maria Luisa
Balcells, Susana
Langdahl, Bente L
Lips, Paul
Lorenc, Roman
Obermayer-Pietsch, Barbara
Scollen, Serena
Bustamante, Mariona
Husted, Lise Bjerre
Carey, Alisoun H
Diez-Perez, Adolfo
Dunning, Alison M
Falchetti, Alberto
Karczmarewicz, Elzbieta
Kruk, Marcin
van Leeuwen, Johannes P. T. M
van Meurs, Joyce B. J
Mangion, Jon
McGuigan, Fiona E. A
Mellibovsky, Leonardo
del Monte, Francesca
Pols, Huibert A. P
Reeve, Jonathan
Reid, David M
Renner, Wilfried
Rivadeneira, Fernando
van Schoor, Natasja M
Sherlock, Rachael E
Ioannidis, John P. A
Genetic markers for osteoporosis study group #
Contributors: Boonen, Steven
Issue Date: Apr-2006
Publisher: Public library science
Series Title: Plos medicine vol:3 issue:4 pages:515-523
Abstract: Background Osteoporosis and fracture risk are considered to be under genetic control. Extensive work is being performed to identify the exact genetic variants that determine this risk. Previous work has suggested that a G/T polymorphism affecting an Sp1 binding site in the COLIA1 gene is a genetic marker for low bone mineral density (BMD) and osteoporotic fracture, but there have been no very-large-scale studies of COLIA1 alleles in relation to these phenotypes.
ISSN: 1549-1676
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gerontology and Geriatrics
× corresponding author
# (joint) last author

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