Title: Fetoscopy-guided fetal endoscopy in a sheep model
Authors: Luks, F I ×
Deprest, Jan
Vandenberghe, K
Laermans, I
De Simpelaere, L
Brosens, I A
Lerut, Antoon #
Issue Date: Jun-1994
Series Title: Journal of the American College of Surgeons vol:178 issue:6 pages:609-12
Abstract: Video-endoscopic surgical treatment of the fetus may, in the future, become an alternative to open fetal operation. Six 95-day-old fetal lambs were examined through intrauterine endoscopy using amnioinfusion and specially designed balloon-tipped cannulas. The fetuses were monitored endoscopically for oxygen saturation, heart rate and temperature throughout the procedure. With a rigid 5 millimeter telescope and a flexible 3 millimeter endoscope, the respiratory and upper gastrointestinal tracts could be examined. No mucosal or other trauma was noted upon completion of the endoscopy; all lambs survived the procedure. While the applications of fetal endosurgery are likely to be similar to those of open fetal operation, fetal endoscopy (looking in the fetus) is a new entity for which clinical relevance (rather than mere feasibility) remains to be demonstrated. This technique, however, could become a valuable research tool to study fetal gastrointestinal and pulmonary physiologic factors in situ.
ISSN: 1072-7515
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Thoracic Surgery
Foetal Medicine Section (-)
× corresponding author
# (joint) last author

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