Journal of orthopaedic rheumatology vol:8 issue:3 pages:127-133
The age-related decline in muscle function is of particular clinical significance, as muscle weakness in the elderly represents one of the main risk factors for senile (type II) osteoporosis. This association is mediated by the effect of muscle function on the incidence and impact of falls, as well as on femoral. bone loss. The age-associated loss of strength is potentially reversible. Resistive training has been documented to increase muscle mass and strength in the elderly, even among frail residents of nursing homes. Vitamin D, growth hormone and testosterone substitution, on the other hand, require further study as potential strategies for attenuating or reversing age-related muscle loss. In addition, prospective studies are needed to support muscle strengthening as a preventive strategy for senile osteoporosis.