Title: Ultrasound assessment of endometrial thickness and endometrial polyps in women on hormonal replacement therapy
Authors: Van den Bosch, Thierry ×
Van Schoubroeck, Dominique
Ameye, Lieveke
De Brabanter, Joseph
Van Huffel, Sabine
Timmerman, Dirk #
Issue Date: May-2003
Series Title: American Journal of Obstetrics and Gynecology vol:188 issue:5 pages:1249-1253
Abstract: OBJECTIVE: This study was performed to evaluate the thickness and the sonographic features of the endometrium in postmenopausal women on hormone replacement therapy (HRT). STUDY DESIGN: This prospective study was based on 483 vaginal ultrasound examinations performed in 238 consecutive postmenopausal women on HRT. RESULTS: Endometrial polyps were diagnosed by ultrasound in 16.3% of the patients; 43.6% were asymptomatic. In the nonpolyp group, a significant difference in endometrial thickness between sequential and continuous schemes was found. In sequential HRT, a three-layer ultrasound pattern of the endometrium was seen in 47% of the women in the estrogen-alone phase of cycle versus 11% in the estrogen-progestogen phase. CONCLUSION: Patients on HRT need other reference values for endometrial thickness compared with postmenopausal women without HRT. In women on sequential HRT, a transvaginal sonographic evaluation performed in the estrogen-alone phase of cycle may optimize the accuracy for focal lesion detection. The significance of the incidental finding of polyps in an important number of asymptomatic women on HRT remains unsettled.
ISSN: 0002-9378
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
Section Woman - Miscellaneous (-)
Basic Research in Gynaecology Section (-)
Technologiecluster ESAT Elektrotechnische Engineering
Electrical Engineering (ESAT) TC, Technology Campuses Ghent and Aalst
× corresponding author
# (joint) last author

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