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Title: Comparative activity of piperacillin/tazobactam against 5625 isolates from hospitalised patients. Multicentre Study Group
Authors: Verbist, Ludo
Verhaegen, Jan
Wouters, C
Vandenhoven, G #
Issue Date: Feb-1996
Series Title: The Journal of antimicrobial chemotherapy vol:37 issue:2 pages:285-93
Abstract: The comparative activities of piperacillin/tazobactam and other antibiotics against 5625 Gram-negative and Gram-positive bacteria freshly isolated from hospitalized patients was examined. The percentage of Enterobacteriaceae susceptible to piperacillin/tazobactam, ceftazidime, imipenem and ciprofloxacin was very similar and varied from 81% to 84% in the Enterobacteriaceae with inducible type 1 beta-lactamases and from 93 to 97% in the non-inducible organisms. Piperacillin/tazobactam was similar in activity to ceftazidime against Pseudomonas aeruginosa and more active than imipenem or ciprofloxacin. Piperacillin/tazobactam is more active than ceftazidime against Gram-positive bacteria (staphylococci, enterococci) and seems to be a promising antibiotic for nosocomial infections.
URI: 
ISSN: 0305-7453
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical Bacteriology and Mycology
# (joint) last author

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