This item still needs to be validated !
Title: Remifentanil for foetal immobilisation and maternal sedation during endoscopic treatment of twin-to-twin transfusion syndrome : a preliminary dose-finding study
Authors: Missant, C ×
Van Schoubroeck, Dominique
Deprest, Jan
Devlieger, Roland
Teunkens, A
Van De Velde, Marc #
Issue Date: Jan-2004
Series Title: Acta Anaesthesiologica Belgica vol:55 issue:3 pages:239-244
Abstract: Twin to twin transfusion syndrome (TTTS) affects 10 to 15% of monochorionic twin pregnancies. Untreated, perinatal loss exceeds 80%, of which survivors have a great risk for long-term neurological disorders as psychomotor retardation or cerebral palsy. TTTS can be treated using foetoscopy and selective ablation of the twin-to-twin blood vessels under local or regional anaesthesia. However, local or regional anaesthesia does not always result in excellent maternal comfort, nor does it provide foetal immobilisation, necessary for optimal surgical conditions. Using a continuous infusion rate of remifentanil 0.1 microg/kg/min, perfect foetal immobilisation and excellent maternal sedation was achieved. Only mild respiratory acidosis was observed as a result of mild respiratory depression. In no mother apnoe occurred. All haemodynamic parameters, both foetal and maternal, remained stable during the procedure. Maternal sedation, respiratory depression and foetal immobilisation were quickly reversible following cessation of the remifentanil infusion.
ISSN: 0001-5164
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Woman - Miscellaneous (-)
Anesthesiology and Algology
Foetal Medicine Section (-)
Pathophysiology of Pregnancy Section (-)
Basic Research in Gynaecology Section (-)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.