Title: Synthesis of ring-expanded aza-analogues of bisbenzocyclooctadiene lignan lactones
Authors: Donets, Pavel Alexandrovich ×
Van der Eycken, Erik #
Issue Date: Dec-2007
Publisher: Wiley-v c h verlag gmbh
Series Title: QSAR & Combinatorial Science vol:26 issue:11-12 pages:1239-1242
Abstract: We report a novel microwave-assisted protocol for the synthesis of hitherto unknown 11-membered ring lignan lactone aza-analogues. The two key steps involve the formation of the biaryl fragment using a microwave-assisted Suzuki-Miyaura cross-coupling reaction and a thermal 1,3-dipolar Huisgen cycloaddition reaction for the introduction of the 1,2,3-triazole ring rendering the cyclized compound.
ISSN: 1611-020X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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