Title: Efficient one-pot, two-step, microwave-assisted procedure for the synthesis of polysubstituted 2-aminoimidazoles
Authors: Ermolat'ev, Denis S ×
Babaev, Eugene V
Van der Eycken, Erik #
Issue Date: Dec-2006
Publisher: Amer chemical soc
Series Title: Organic letters vol:8 issue:25 pages:5781-5784
Abstract: A microwave-assisted, one- pot, two-step protocol was developed for the construction of polysubstituted 2-aminoimidazoles. This process involves the sequential formation of imidazo[1,2-a]pyrimidinium salts from readily available 2-aminopyrimidines and alpha-bromocarbonyl compounds, followed by opening of the pyrimidine ring with hydrazine.
ISSN: 1523-7060
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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