Title: A novel, microwave-assisted method for the synthesis of alicyclic-condensed 5H-1,4,6,7-tetrahydro-1,4-diazepin-5-ones
Authors: Balazs, Arpad ×
Van der Eycken, Erik
Fulop, Ferenc #
Issue Date: Jul-2008
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:49 issue:28 pages:4333-4335
Abstract: An efficient, high-yielding method has been developed for the synthesis of cycloalkane-fused and phenyl-substituted 1,4-diazepin-5-ones from beta-amino acids. The process involves the oxidative cleavage of a terminal olefin bond and an acid-catalyzed, microwave-assisted intramolecular condensation step. (C) 2008 Published by Elsevier Ltd.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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