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Title: Previously Untreated Adenocarcinoma of the paranasal sinuses: results of endoscopic resection followed by radiotherapy
Authors: Vander Poorten, Vincent
Bogaerts, Sofie
Nuyts, Sandra
Van den Bogaert, Walter
Jorissen, Mark #
Issue Date: 21-Jul-2008
Host Document: Abstract Book – Proceedings of the 7th International Conference on Head and Neck Cancer – American Head and Neck Society
Conference: 7th International Conference on Head and Neck Cancer edition:7 location:San Francisco date:19-22 July 2008
Article number: P 208
Abstract: Objectives: Adenocarcinoma is the most frequent paranasal sinus malignancy in Belgium. Classically patients with this disease are treated by an external surgical approach (lateral rhinotomy with medial maxillectomy or craniofacial resection) followed by radiotherapy. The role, possibilities, and limitations of endoscopic sinus surgery (ESS) in this treatment protocol remain to be established.
Methods: We studied 44 patients with a new diagnosis of adenocarcinoma, treated with ESS and radiotherapy between 1992 and 2004.
Results: The median follow-up of the patients alive at the end of the study period was 36 months. For the 3-year follow-up, the overall survival, disease-specific survival, and local control rate were 81%, 91%, and 73%, respectively. Corresponding rates for the 5-year follow-up were 53%, 83%, and 62%. International Union Against Cancer T classification did not appear to influence these results.
Conclusions: ESS followed by radiotherapy for primary adenocarcinoma of the paranasal sinuses gives oncological results in the range of those of standard external approaches
Publication status: published
KU Leuven publication type: IMa
Appears in Collections:Research Group Experimental Oto-rhino-laryngology
Laboratory of Experimental Radiotherapy
Head and Neck Oncology (+)
# (joint) last author

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