Title: Identification of patients with Salivary Gland Cancer at risk for Short Term Mortality
Authors: Baatenburg de Jong, Robert
van der Schroeff, Marc
Steyerberg, Eric
Vander Poorten, Vincent
Terhaard, Chris #
Issue Date: 19-Oct-2007
Conference: Second International Congress on Salivary Gland Diseases edition:2 location:Pittsburgh date:19-21 October 2007
Abstract: Title: Can we identify patients with salivary cancer at risk for short-term mortality?
Objective: To develop a prognostic model for mortality within the first year after treatment.
Materials and methods: a nationwide cohort of 666 patients with a malignant salivary gland tumor was analyzed to assess the prognostic value of different clinical parameters. Patients were derived from all university hospitals in the Netherlands. All parameters were included in the multivariate analysis. The prognostic power was measured with a ROC-curve.
Results: Significant in multivariate analysis were pre-treatment pain, size of the tumor, nodal status and age. Skin invasion, localization of the tumor and co-morbidity were not significant. All variables were entered in a logistic regression model. The area under the curve (ROC) was .83, representing high predictive power.
Conclusion: The presented prognostic model provides a reliable short-term prognosis for patients with a malignant salivary gland tumor. Palliative rather than curative treatment should be considered for patients with expected high short-term mortality.
Publication status: published
KU Leuven publication type: IMa
Appears in Collections:Research Group Experimental Oto-rhino-laryngology
Head and Neck Oncology (+)
# (joint) last author

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