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Title: Effect of low-dose testosterone treatment on craniofacial growth in boys with delayed puberty
Authors: Verdonck, Anna ×
Gaethofs, M
Carels, Carine
de Zegher, Francis #
Issue Date: Apr-1999
Series Title: European journal of orthodontics vol:21 issue:2 pages:137-43
Abstract: Craniofacial growth was investigated in boys treated with low-dose testosterone for delayed puberty (> 14 years old; testicular volume < 4 ml; n = 7) and compared with controls (12-14 years; n = 37). Cephalometric radiographs, statural height and pubertal stage were recorded at the start of the study and after 1 year. Craniofacial growth was assessed by nine linear measurements. At the beginning of the study, statural height, mandibular ramus length, upper anterior face height, and total cranial base length were significantly shorter in the delayed puberty boys than in the controls. After 1 year, the growth rate of the statural height, total mandibular length, ramus length, and upper and total anterior face height was significantly higher in the treated boys than in the untreated height-matched controls (n = 7). The craniofacial measurements were similar in the treated boys as compared with the controls. These results show that statural height and craniofacial dimensions are low in boys with delayed puberty. Low doses of testosterone accelerate statural and craniofacial growth, particularly in the delayed components, thus leading towards a normalization of facial dimensions.
URI: 
ISSN: 0141-5387
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Interdisciplinary Research Facility Life Sciences, Campus Kulak Kortrijk
Orthodontics
Section Newborn (-)
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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